Late-onset Warfarin Induced Skin Necrosis: In a Hemodialysis Patient

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Late-onset Warfarin Induced Skin Necrosis: In a Hemodialysis Patient

Chronic dialysis patients frequently present with necrotic skin lesions. The differential diagnoses are broad and complex. The main focus of this paper is differentiating features of two diagnostic entities: Warfarin induced skin necrosis and calciphylaxis as early recognition and treatment may prevent the significant mortality. We discuss a case involving a hemodialysis patient, who developed ...

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Late-onset Warfarin Induced Skin Necrosis: In a Hemodialysis Patient

Chronic dialysis patients frequently present with necrotic skin lesions. The differential diagnoses are broad and complex. The main focus of this paper is differentiating features of two diagnostic entities: Warfarin induced skin necrosis and calciphylaxis as early recognition and treatment may prevent the significant mortality. We discuss a case involving a hemodialysis patient, who developed ...

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Warfarin-Induced Skin Necrosis

Warfarin-induced skin necrosis is an infrequent complication occurring in individuals under warfarin treatment who have a thrombophilic history or after administration of large loading doses of warfarin particularly without simultaneous initial use of heparin. A 62-year-old lady developed skin necrosis 4 days after initiating warfarin therapy of 5 mg daily without initial co-administration of h...

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Warfarin induced skin necrosis in a patient with craniopharyngioma.

Oral anticoagulants are associated with several adverse skin manifestations ranging from ecchymosis, purpura, and hemorrhagic necrosis to maculopapular rash, vesicular urticarial eruptions and purple toes. Skin necrosis is a rare but serious side effect of warfarin therapy, associated with significant morbidity and mortality. The prevalence of warfarin induced skin necrosis (WISN) is 0.01-0.1%....

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Skin necrosis is a rare complication of warfarin therapy that occurs between the third and 10th days of treatment. The pathogenesis of warfarin-induced skin necrosis is attributable to the emergence of a transient hypercoagulable state. The condition most commonly involves skin areas with abundant subcutaneous adipose tissue such as the breasts, buttocks, abdomen, thighs, and the extremities. W...

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ژورنال

عنوان ژورنال: Journal of Kidney

سال: 2017

ISSN: 2472-1220

DOI: 10.4172/2472-1220.1000141